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BIO316 8/10

1. Protein Sequence and Structure was compiled as Atlas of Protein Sequence and Structure by
Dayhoff and co-workers in 1965

2. The full meaning of ExPASy is
Expert Protein Analysis System

3. The two main databases that are widely used for novel gene discovery are
High-throughput genomic and Expressed sequence tag databases

4. A table of matrix representing a visual representation of similarities between two sequences is the
Dotplot Analysis

5. Protein Information Resource (PIR) was established by one of the following bodies
National Biomedical Research Foundation

6. Structural classification of proteins in which the proteins are classified into hierarchy such as classes, folds, super-families is obtained in the
SCOP

7. All the following are componenets of Proteomics analysis except
Determination of amino acid composition

8. Three databases, DDBJ, EMBL and GenBank act together in collecting and distributing sequences so that each has copies of all the sequences, thus they act as
primary distribution centre for sequences

9. The version of BLAST that searches a protein sequence against a protein database is the
BLASTP

10. The remarkable development in the field of bioinformatics in the year 1988 was
development of computer methods pioneered by Dayhoff and her research group