Q1 The alkylation and arylaton of to cause motations is part of the toxicodynamic phase
Q2 A mutated cells does not necessarily form a
Q3 Depression of the system will lower resistance to infectious disease and facilitate the development of
Q4 Ozone irritates the eyes, upper respiratory system and
Q5 Elemental mercury may be absorbed by biological system as a
Q6 are the suspended liquid droplets generated by condensation from the gaseous to the liquid state.
Q7 means that the action takes place at the point or area of contact.
Q8 Acetylene is a colourless gas with a odour
Q9 Inhaled benzene is readily absorbed by the blood from which it is taken up by
Q10 The toxicological property of _are very similar to ethylene
Q11 Exposure to n-hexane and cyclohexane result in loss of myelin and degeneration of
Q12 is term will be used in contrast to acute exposure and it is of long duration.
Q13 refers to a site of action other than the point of contact and presupposes that absorption has taken place.
Q14 Toxicants can cause _which is the impairment of the body's natural defense mechanisms
Q15 is the stage in which the neoplastic cells become a malignant tumour
Q16 Ludwig Rehn reported elevated incidences of bladder cancer in dye workers exposed to chemicals extracted from
Q17 Nitrite can convert haemoglobin to
Q18 Toxicants have the same effect on organisms (True or False)
Q19 The primary risk associated with 2,4-D and 2,4,5-T was due to the presence small amounts of dioxin
Q20 Pyrethroids that have Peripherial CNS effects are known as
Q21 The toxicological properties of are very similar to those of ethylene
Q22 is a widely used colourless gas that acts as an anesthetic to animals and is toxic to plants
Q23 is a metalloid which forms a number of toxic compounds
Q24
is a metal which is widely used in industries, in alloys, in plating,
in batteries and in the pigment in inks, paints, plastics, rubber and
enamel
Q25 Lead and most of the heavy metals have effect on the (PNS) or the (CNS)
Q26 has been known to be a poisonous compound for centuries
Q27 The micro-organisms in the sediments at the bottom bio-transformed the organic mercury ions methyl and mercury
Q28 Organic mercury such as, methylmecury, is extremely toxic mainly
affecting the central nervous system in Japan caused a disease known as
Q29 is measured by octanol:- water partition coefficient in a separatory funnel
Q30 The rate of extent of absorbtion of hydrophobic chemicals depends of these factors except
Q31 the outer most corny layer of the skin plays an important role in determining the permeability of this layer
Q32 The involved as protective covering against a hostile environment and is relectively impermeable to many chemical
Q33 During the Phase I reactions an OH group is attached to benzene to change it to
Q34 Chemical species that cause birth defects are known as
Q35 7.8-diol-9,10-epoxide of benzo[a]pyrene is not a carcinogen. True or False
Q36 refers to a single exposure of duration measure in second minutes or hours
Q37 Following the WHO Recommended Classification of Pesticides by hazard ,slightly hazardous are in CLASS
Q38 Dose-response relationship is a major concept of
Q39 Hydrophilic compounds become lipophilic during the Phase I reactions True or False.
Q40 What does NOEL stand for?
Q41 The stage in which the cancerous cells become a malignant tumour during the carcinogenic process is known as the
Q42 is used to treat seed grain
Q43 Ingestion of __can cause black sore syndrome in Turkey
Q44 Weak bases concentrate in areas of lower pH True or False ;
Q45 “All things are poison and nothing is without poison; only the dose makes a thing a poison “ is a statement credited to:
Q46 When a toxic effect occurs at the point or area of contact of the toxin, what type of effect is it said to have?
Q47 Poisonous plants and are extracted for hunting and warfare
Q48 The historical development of toxicology began with _dwellers
Q49 Phase II reaction are also known as
Q50 Pesticides are chemicals that are use to kill
Q51 Many pesticides in use have different modes of action and levels of
Q52 The concept that at extremely low dose, a given substance may be
non-toxic and even beneficial while at intermediate dose, it may be
toxic is
Q53 Berylliosis a condition manifested by lung fibrosis and phenumonitis toxicity of the element
Q54 __is the unrestrained, malignant proliferation of somatic cell
Q55 Exposure to lead may lead to anemia True or False
Q56 Acetylcholine, a major neurotransmitterin animals is normallyrapidly deactivated by an enzyme called
Q57 What term is used to indicate the ability of a cancer to invade other parts of the body and produce secondary tumours
Q58 Pyrethroids fall into two categories based on their acute
Q59 Hexachlorobezene studies in rats also provide evidence of
Q60 Fungicides have the potential to be __based on their mutagenic activity
Q61 Ozone can cause all but one of the following effects :
Q62 One of these is not true of nicotine.
Q63 One of these substances can easily be absorbed by the skin:
Q64 One of these methods of transportation through membranes does not involve specialized transport
Q65 Which of these statements is not true of the enzymes Cytochrome PN450
Q66 Alcohols can lead to all but one of the following effects
Q67 One of these substances is not colourless.
Q68 Which of these events occurred in the 17th Century?
Q69 Which of these events did not occur in the 19th Century
Q70 One of these is not a constituent of Bordeaux mixture
Q71 Which of these is not a rodenticides?
Q72 All but one of these are groups of insecticides.
Q73 Which of the following is the basic mechanism of action of insecticides?
Q74 Which of these insecticides can be categorised as High toxic potential insecticide?
Q75 Which of these is not true of DDT?
Q76 Which of these statements is NOT true of synthetic pyrethroids ?
Q77 Which of these statements is NOT true of Rotenone ?
Q78 Which of these is NOT true of Paraquat
Q79 Which of these is NOT a symptom associated with back sore syndrome
Q80 Which of these pesticides mimics the action of Acetylcholine
Q81 One of these substances is a waste from leather products manufacturing industries
Q82 Exposure to Toluene may lead to one of the following effects:
Q83 Ingestion of_____can caused black sore syndrome in Turkey
Q84 The inhalation of air containing benzene can lead to the following progressive effects:
Q85 Acute toxicity generally very low in
Q86 One of these substances can cause spontaneous abortion when inhaled:
Q87 Ozone can cause all but one of the following effects :
Q88 The historical development of toxicology began with____dwellers
Q89 One of these is not a heavy metal
Q90 Pesticides are chemicals that are use to kill
Q91 Many pesticides in use have different modes of action and levels of
Q92 Which conjugation reaction decreases, instead of increases, water solubility?
Q93 The rate and extent of absorption of hydrophobic chemicals depends on all but one of these
Q94 _____is the unrestrained, malignant proliferation of somatic cell
Q95 DDT is a____ pesticide
Q96 Acetylcholine, a major neurotransmitterin animals is normallyrapidly deactivated by an enzyme called
Q97 _______ = Concentration x Exposure
Q98 Pyrethroids fall into two categories based on their acute
Q99 Absorption through the skin is promoted by all these except
Q100 All but one of these is true of active transport
Q101 The toxicological properties of _________ are very similar to those of ethylene
Q102 _________ is a widely used colourless gas that acts as an anesthetic to animals and is toxic to plants
Q103 ___________ is a metalloid which forms a number of toxic compounds
Q104 _________ is a metal which is widely used in
industries, in alloys, in plating, in batteries and in the pigment in
inks, paints, plastics, rubber and enamel
Q105 Lead and most of the heavy metals have __________ effect on the (PNS) or the (CNS)
Q106 __________ has been known to be a poisonous compound for centuries
Q107 The micro-organisms in the sediments at the
bottom bio-transformed the organic mercury ions methyl and ___________
mercury
Q108 Which of these substances caused the disease, Minamata in Japan
Q109 The four routes of entry are:
Q110 The rate of extent of absorption of hydrophobic chemicals depends of these factors except
Q111 One of these can be classified as a chronic illness
Q112 An exposure which would be relatively harmless unless repeated over a long period of time
Q113 One of these is not of importance in the
conduct of risk assessments.
Q114 Which of these statements is not true of dose- response relationship ?
Q115 All but one of these defines toxicology:
Q116 _________ refers to a single exposure of duration measure in second minutes or hours
Q117 One of these areas of toxicology involves
toxicologists with specialised knowledge of law working with pathologist
to establish cases
Q118 Toxicology integrates with all but one of these fields;
Q119 One of these definitions is known as "the traditional definition of toxicology"
Q120 One of these scientists prepared a systematic
correlation between the chemical and biological properties of poisons of
his time